@layer quartz-base{@keyframes dropin{0%{opacity:0;visibility:hidden}1%{opacity:0}to{opacity:1;visibility:visible}}.popover{z-index:999;will-change:transform;padding:1rem;position:fixed;top:0;left:0;overflow:visible}.popover>.popover-inner{width:30rem;max-height:20rem;font-weight:initial;font-style:initial;line-height:normal;font-size:initial;font-family:var(--bodyFont);border:1px solid var(--lightgray);background-color:var(--light);overscroll-behavior:contain;white-space:normal;-webkit-user-select:none;user-select:none;cursor:default;border-radius:5px;padding:0 1rem 1rem;position:relative;overflow:auto;box-shadow:6px 6px 36px #00000040}.popover>.popover-inner[data-content-type][data-content-type*=pdf],.popover>.popover-inner[data-content-type][data-content-type*=image]{max-height:100%;padding:0}.popover>.popover-inner[data-content-type][data-content-type*=image] img{border-radius:0;margin:0;display:block}.popover>.popover-inner[data-content-type][data-content-type*=pdf] iframe{width:100%}.popover h1{font-size:1.5rem}.popover{visibility:hidden;opacity:0;transition:opacity .3s,visibility .3s}@media (max-width:800px){.popover{display:none!important}}.active-popover,.popover:hover{animation:.3s .2s forwards dropin}code[data-theme*=\ ]{color:var(--shiki-light);background-color:var(--shiki-light-bg)}code[data-theme*=\ ] span{color:var(--shiki-light)}[saved-theme=dark] code[data-theme*=\ ]{color:var(--shiki-dark);background-color:var(--shiki-dark-bg)}[saved-theme=dark] code[data-theme*=\ ] span{color:var(--shiki-dark)}.callout{border:1px solid var(--border);background-color:var(--bg);box-sizing:border-box;border-radius:5px;padding:0 1rem;overflow-y:hidden}.callout>.callout-content{transition:grid-template-rows .1s cubic-bezier(.02,.01,.47,1);display:grid;overflow:hidden}.callout>.callout-content>:first-child{margin-top:0}.callout{--callout-icon-note:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><line x1=\"18\" y1=\"2\" x2=\"22\" y2=\"6\"></line><path d=\"M7.5 20.5 19 9l-4-4L3.5 16.5 2 22z\"></path></svg>");--callout-icon-abstract:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><rect x=\"8\" y=\"2\" width=\"8\" height=\"4\" rx=\"1\" ry=\"1\"></rect><path d=\"M16 4h2a2 2 0 0 1 2 2v14a2 2 0 0 1-2 2H6a2 2 0 0 1-2-2V6a2 2 0 0 1 2-2h2\"></path><path d=\"M12 11h4\"></path><path d=\"M12 16h4\"></path><path d=\"M8 11h.01\"></path><path d=\"M8 16h.01\"></path></svg>");--callout-icon-info:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><circle cx=\"12\" cy=\"12\" r=\"10\"></circle><line x1=\"12\" y1=\"16\" x2=\"12\" y2=\"12\"></line><line x1=\"12\" y1=\"8\" x2=\"12.01\" y2=\"8\"></line></svg>");--callout-icon-todo:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22c5.523 0 10-4.477 10-10S17.523 2 12 2 2 6.477 2 12s4.477 10 10 10z\"></path><path d=\"m9 12 2 2 4-4\"></path></svg>");--callout-icon-tip:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M8.5 14.5A2.5 2.5 0 0 0 11 12c0-1.38-.5-2-1-3-1.072-2.143-.224-4.054 2-6 .5 2.5 2 4.9 4 6.5 2 1.6 3 3.5 3 5.5a7 7 0 1 1-14 0c0-1.153.433-2.294 1-3a2.5 2.5 0 0 0 2.5 2.5z\"></path></svg> ");--callout-icon-success:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"20 6 9 17 4 12\"></polyline></svg> ");--callout-icon-question:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><circle cx=\"12\" cy=\"12\" r=\"10\"></circle><path d=\"M9.09 9a3 3 0 0 1 5.83 1c0 2-3 3-3 3\"></path><line x1=\"12\" y1=\"17\" x2=\"12.01\" y2=\"17\"></line></svg> ");--callout-icon-warning:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"m21.73 18-8-14a2 2 0 0 0-3.48 0l-8 14A2 2 0 0 0 4 21h16a2 2 0 0 0 1.73-3Z\"></path><line x1=\"12\" y1=\"9\" x2=\"12\" y2=\"13\"></line><line x1=\"12\" y1=\"17\" x2=\"12.01\" y2=\"17\"></line></svg>");--callout-icon-failure:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><line x1=\"18\" y1=\"6\" x2=\"6\" y2=\"18\"></line><line x1=\"6\" y1=\"6\" x2=\"18\" y2=\"18\"></line></svg> ");--callout-icon-danger:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polygon points=\"13 2 3 14 12 14 11 22 21 10 12 10 13 2\"></polygon></svg> ");--callout-icon-bug:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><rect width=\"8\" height=\"14\" x=\"8\" y=\"6\" rx=\"4\"></rect><path d=\"m19 7-3 2\"></path><path d=\"m5 7 3 2\"></path><path d=\"m19 19-3-2\"></path><path d=\"m5 19 3-2\"></path><path d=\"M20 13h-4\"></path><path d=\"M4 13h4\"></path><path d=\"m10 4 1 2\"></path><path d=\"m14 4-1 2\"></path></svg>");--callout-icon-example:url("data:image/svg+xml; utf8,<svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><line x1=\"8\" y1=\"6\" x2=\"21\" y2=\"6\"></line><line x1=\"8\" y1=\"12\" x2=\"21\" y2=\"12\"></line><line x1=\"8\" y1=\"18\" x2=\"21\" y2=\"18\"></line><line x1=\"3\" y1=\"6\" x2=\"3.01\" y2=\"6\"></line><line x1=\"3\" y1=\"12\" x2=\"3.01\" y2=\"12\"></line><line x1=\"3\" y1=\"18\" x2=\"3.01\" y2=\"18\"></line></svg> ");--callout-icon-quote:url("data:image/svg+xml; utf8, <svg xmlns=\"http://www.w3.org/2000/svg\" width=\"100%\" height=\"100%\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 21c3 0 7-1 7-8V5c0-1.25-.756-2.017-2-2H4c-1.25 0-2 .75-2 1.972V11c0 1.25.75 2 2 2 1 0 1 0 1 1v1c0 1-1 2-2 2s-1 .008-1 1.031V20c0 1 0 1 1 1z\"></path><path d=\"M15 21c3 0 7-1 7-8V5c0-1.25-.757-2.017-2-2h-4c-1.25 0-2 .75-2 1.972V11c0 1.25.75 2 2 2h.75c0 2.25.25 4-2.75 4v3c0 1 0 1 1 1z\"></path></svg>");--callout-icon-fold:url("data:image/svg+xml,%3Csvg xmlns=\"http://www.w3.org/2000/svg\" width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"%3E%3Cpolyline points=\"6 9 12 15 18 9\"%3E%3C/polyline%3E%3C/svg%3E")}.callout[data-callout]{--color:#448aff;--border:#448aff44;--bg:#448aff10;--callout-icon:var(--callout-icon-note)}.callout[data-callout=abstract]{--color:#00b0ff;--border:#00b0ff44;--bg:#00b0ff10;--callout-icon:var(--callout-icon-abstract)}.callout[data-callout=info],.callout[data-callout=todo]{--color:#00b8d4;--border:#00b8d444;--bg:#00b8d410;--callout-icon:var(--callout-icon-info)}.callout[data-callout=todo]{--callout-icon:var(--callout-icon-todo)}.callout[data-callout=tip]{--color:#00bfa5;--border:#00bfa544;--bg:#00bfa510;--callout-icon:var(--callout-icon-tip)}.callout[data-callout=success]{--color:#09ad7a;--border:#09ad7144;--bg:#09ad7110;--callout-icon:var(--callout-icon-success)}.callout[data-callout=question]{--color:#dba642;--border:#dba64244;--bg:#dba64210;--callout-icon:var(--callout-icon-question)}.callout[data-callout=warning]{--color:#db8942;--border:#db894244;--bg:#db894210;--callout-icon:var(--callout-icon-warning)}.callout[data-callout=failure],.callout[data-callout=danger],.callout[data-callout=bug]{--color:#db4242;--border:#db424244;--bg:#db424210;--callout-icon:var(--callout-icon-failure)}.callout[data-callout=bug]{--callout-icon:var(--callout-icon-bug)}.callout[data-callout=danger]{--callout-icon:var(--callout-icon-danger)}.callout[data-callout=example]{--color:#7a43b5;--border:#7a43b544;--bg:#7a43b510;--callout-icon:var(--callout-icon-example)}.callout[data-callout=quote]{--color:var(--secondary);--border:var(--lightgray);--callout-icon:var(--callout-icon-quote)}.callout.is-collapsed>.callout-title>.fold-callout-icon{transform:rotate(-90deg)}.callout.is-collapsed 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var(--icon-size);padding:.2rem 0;-webkit-mask-position:50%;mask-position:50%;-webkit-mask-repeat:no-repeat;mask-repeat:no-repeat}.callout-title .callout-title-inner{font-weight:600}html{scroll-behavior:smooth;-webkit-text-size-adjust:none;-moz-text-size-adjust:none;text-size-adjust:none;width:100vw;overflow-x:hidden}@media (max-width:800px){html{scroll-padding-top:4rem}}body{box-sizing:border-box;background-color:var(--light);font-family:var(--bodyFont);color:var(--darkgray);margin:0}.text-highlight{background-color:var(--textHighlight);border-radius:5px;padding:0 .1rem}::selection{background:color-mix(in srgb, var(--tertiary) 60%, #fff0);color:var(--darkgray)}p,ul,text,a,tr,td,li,ol,ul,.katex,.math,.typst-doc,g[class~=typst-text]{color:var(--darkgray);fill:var(--darkgray);overflow-wrap:break-word;text-wrap:pretty}path[class~=typst-shape]{stroke:var(--darkgray)}.math.math-display{text-align:center}article>mjx-container.MathJax,article 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.2rem;position:relative;transform:translateY(2px)}input[type=checkbox]:checked{border-color:var(--secondary);background-color:var(--secondary)}input[type=checkbox]:checked:after{content:"";border:solid var(--light);border-width:0 2px 2px 0;width:4px;height:8px;display:block;position:absolute;top:1px;left:4px;transform:rotate(45deg)}blockquote{border-left:3px solid var(--secondary);margin:1rem 0;padding-left:1rem;transition:border-color .2s}h1,h2,h3,h4,h5,h6,thead{font-family:var(--headerFont);color:var(--dark);font-weight:revert;margin-bottom:0}article>h1>a[role=anchor],article>h2>a[role=anchor],article>h3>a[role=anchor],article>h4>a[role=anchor],article>h5>a[role=anchor],article>h6>a[role=anchor],article>thead>a[role=anchor]{color:var(--dark);background-color:#0000}h1[id]>a[href^=\#],h2[id]>a[href^=\#],h3[id]>a[href^=\#],h4[id]>a[href^=\#],h5[id]>a[href^=\#],h6[id]>a[href^=\#]{opacity:0;font-family:var(--codeFont);-webkit-user-select:none;user-select:none;margin:0 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[style*="color:#f2ce5a"]{color:var(--orx-mol-yellow)!important}.orx-molecules-index__divider{border:0;border-top:1px solid var(--orx-mol-border);margin:30px 0}.orx-molecules-index__resource-title{color:var(--orx-mol-muted);text-transform:uppercase;letter-spacing:2px;margin-bottom:20px;font-size:.9em}.orx-molecules-index .orx-molecules-index__resource-card{background:var(--orx-mol-card)}.orx-glossary{max-width:100%}.orx-glossary__hero,.orx-glossary__section,.orx-glossary__sources{border:1px solid var(--orx-mol-border);background:color-mix(in srgb, var(--light) 82%, transparent);border-radius:16px;margin:1.4rem 0;padding:clamp(1.2rem,3vw,2rem)}.orx-glossary__hero{border-top:3px solid var(--orx-mol-purple)}.orx-glossary__eyebrow{color:var(--orx-mol-purple);font-family:var(--codeFont);letter-spacing:.12em;text-transform:uppercase;margin:0 0 .5rem;font-size:.76rem;font-weight:800}.orx-glossary__hero h1{color:var(--dark);margin:0 0 .8rem;font-size:clamp(2rem,5vw,3rem)}.orx-glossary__hero p:last-child{color:var(--darkgray);margin-bottom:0;line-height:1.65}.orx-glossary__nav{flex-wrap:wrap;gap:.65rem;margin:1.2rem 0;display:flex}.orx-glossary__nav a{border:1px solid var(--orx-mol-purple);background:color-mix(in srgb, var(--orx-mol-purple) 8%, transparent);min-height:42px;color:var(--dark);border-radius:9px;align-items:center;padding:.55rem .8rem;font-weight:700;text-decoration:none;display:inline-flex}.orx-glossary__nav a:hover{box-shadow:0 0 12px color-mix(in srgb, var(--orx-mol-purple) 38%, transparent)}.orx-glossary__nav a:focus-visible,.orx-glossary a:focus-visible{outline:2px solid var(--orx-mol-yellow);outline-offset:3px}.orx-glossary__section{border-top:3px solid var(--orx-glossary-accent,var(--orx-mol-purple))}.orx-glossary__section--blue{--orx-glossary-accent:var(--orx-mol-blue)}.orx-glossary__section--orange{--orx-glossary-accent:var(--orx-mol-orange)}.orx-glossary__section--green{--orx-glossary-accent:var(--orx-mol-green)}.orx-glossary__section--red{--orx-glossary-accent:var(--orx-mol-red)}.orx-glossary__section h2{color:var(--dark);margin:0 0 .4rem}.orx-glossary__section>p{color:var(--darkgray)}.orx-glossary__terms{grid-template-columns:repeat(auto-fit,minmax(min(100%,280px),1fr));gap:.8rem;margin:1rem 0 0;display:grid}.orx-glossary__term{border:1px solid var(--orx-mol-border);background:var(--orx-mol-card);border-radius:10px;min-width:0;padding:.9rem 1rem;scroll-margin-top:1.5rem}.orx-glossary__term:target{border-color:var(--orx-glossary-accent);box-shadow:0 0 0 2px color-mix(in srgb, var(--orx-glossary-accent) 35%, transparent)}.orx-glossary__term dt{color:var(--orx-glossary-accent);margin-bottom:.3rem;font-weight:850}.orx-glossary__term dd{color:var(--darkgray);margin:0;line-height:1.5}.orx-glossary__kinetics{flex-wrap:wrap;align-items:stretch;gap:.5rem;margin-top:1rem;display:flex}.orx-glossary__kinetics span{color:var(--orx-mol-blue);align-self:center;font-weight:900}.orx-glossary__kinetics div{border:1px solid var(--orx-mol-blue);background:color-mix(in srgb, var(--orx-mol-blue) 8%, transparent);text-align:center;border-radius:9px;flex:150px;padding:.75rem}.orx-glossary__kinetics small{color:var(--orx-mol-muted);display:block}.orx-glossary__sources{border-top:3px solid var(--orx-mol-purple)}.orx-glossary__sources h2{margin-top:0}.orx-glossary__sources li{margin:.5rem 0}.orx-glossary__sources a{color:var(--orx-mol-blue)}article a.eval-action.orx-pharma-glossary-link{border-color:var(--orx-mol-purple,#b392f0);color:var(--dark);background:color-mix(in srgb, var(--light) 85%, transparent)}article a.eval-action.orx-pharma-glossary-link:hover{background:color-mix(in srgb, var(--light) 65%, var(--lightgray));box-shadow:0 0 12px #b392f059}@media (max-width:520px){.orx-molecules-index__glossary{width:100%}.orx-molecules-index .orioris-grid{grid-template-columns:minmax(0,1fr)}}@media (prefers-reduced-motion:reduce){.orx-molecules-index__glossary:hover{transform:none}}:root{--pageWidth:1100px!important}.center,.page>.center,article{max-width:var(--pageWidth)!important;margin:0 auto!important}article iframe,article video{aspect-ratio:16/9;border:1px solid var(--lightgray);border-radius:8px;margin:2rem 0;width:100%!important;max-width:100%!important}@media screen and (max-width:768px){.page,.center,article{padding:0 14px!important}body:before{opacity:.03!important;width:90vw!important;max-width:320px!important}}body{background-color:var(--light);background-color:var(--light);position:relative}body:before{content:"";pointer-events:none;z-index:0;filter:invert();mix-blend-mode:multiply;opacity:.09;background-image:url(/static/Spiral-logo.png);background-position:50%;background-repeat:no-repeat;transition:opacity .3s,filter .3s;position:fixed;top:50%;left:50%;transform:translate(-50%,-50%);background-size:contain!important;width:100vw!important;height:100vh!important}:root[saved-theme=dark] body:before{filter:invert(0);mix-blend-mode:screen;opacity:.075}.page,.center,article{z-index:1;position:relative}body[data-slug=index] .page{max-width:100%!important}body[data-slug=index] .page>#quartz-body{max-width:calc(var(--pageWidth) + 64px);grid-template-columns:minmax(0,1fr);grid-template-areas:"grid-sidebar-left""grid-header""grid-center""grid-footer";margin:0 auto;padding:0 32px;display:grid}body[data-slug=index] .page>#quartz-body>.sidebar.left{flex-direction:row;align-items:center;width:100%;height:auto;min-height:64px;padding:16px 0 8px;display:flex;position:static}body[data-slug=index] .page>#quartz-body>.sidebar.left .page-title{margin:0 auto 0 0}body[data-slug=index] .page>#quartz-body>.sidebar.left .flex-component{flex:0 auto}body[data-slug=index] .page>#quartz-body>.sidebar.right{display:none}body[data-slug=index] .page>#quartz-body>.center,body[data-slug=index] .page>#quartz-body>footer{width:100%;min-width:0}body[data-slug=index] .page>#quartz-body>.center>article{max-width:var(--pageWidth)!important;margin:0 auto!important}body[data-slug=index] .page>#quartz-body>.page-header{margin-top:0}@media screen and (max-width:768px){body[data-slug=index] .page>#quartz-body{padding:0 14px}body[data-slug=index] .page>#quartz-body>.sidebar.left{padding-top:12px}}.page{max-width:100%!important}.page>#quartz-body{max-width:calc(var(--pageWidth) + 64px);grid-template-columns:minmax(0,1fr);grid-template-areas:"grid-sidebar-left""grid-header""grid-center""grid-sidebar-right""grid-footer";margin:0 auto;padding:0 32px;display:grid}.page>#quartz-body>.sidebar.left{flex-direction:row;align-items:center;width:100%;height:auto;min-height:64px;padding:16px 0 8px;display:flex;position:static}.page>#quartz-body>.sidebar.left .page-title{margin:0 auto 0 0}.page>#quartz-body>.sidebar.left .flex-component{flex:0 auto}.page>#quartz-body>.sidebar.right{flex-direction:row;width:100%;height:auto;margin:32px 0 0;padding:0;display:flex;position:static}.page>#quartz-body>.sidebar.right>*{width:100%;max-width:var(--pageWidth);margin:0 auto}.page>#quartz-body>.center,.page>#quartz-body>footer{width:100%;min-width:0}.page>#quartz-body>.center>article{max-width:var(--pageWidth)!important;margin:0 auto!important}.page>#quartz-body>.page-header{margin-top:0}article [style*="background: #000"],article [style*="background:#000"],article [style*="background: #0d1117"],article [style*="background:#0d1117"]{-webkit-backdrop-filter:blur(2px);backdrop-filter:blur(2px);background-color:#0d1117ad!important}article div[style*="background: linear-gradient(145deg"],article div[style*="background:linear-gradient(145deg"],article div[style*="background: #000"],article div[style*="background:#000"],article div[style*="background: #010409"],article div[style*="background:#010409"],article div[style*="background: #0d1117"],article div[style*="background:#0d1117"],article div[style*="background: #161b22"],article div[style*="background:#161b22"]{-webkit-backdrop-filter:blur(2px);backdrop-filter:blur(2px);background:#0d1117ad!important}@media screen and (max-width:768px){.page>#quartz-body{padding:0 14px}.page>#quartz-body>.sidebar.left{padding-top:12px}.page>#quartz-body>.sidebar.right{margin-top:22px}}article a.eval-action{box-sizing:border-box;color:#79c0ff;text-align:center;background:#182b40;border:1px solid #58a6ff;border-radius:8px;justify-content:center;align-items:center;max-width:100%;min-height:44px;margin:5px 8px 5px 0;padding:8px 15px;font-weight:700;text-decoration:none;display:inline-flex}article a.eval-action:hover{background:#233d5b}article a.eval-action:focus-visible{outline-offset:4px;outline:3px solid #f2ce5a}@media (max-width:520px){article a.eval-action{width:100%;margin-right:0}}article.index-cartes-orioris+.page-listing{display:none}.orioris-grid{grid-template-columns:repeat(auto-fit,minmax(200px,1fr));gap:15px;margin-bottom:30px;display:grid}.orioris-box{border:1px solid var(--darkgray);box-sizing:border-box;background:#ffffff05;border-radius:8px;flex-direction:column;height:100%;padding:15px;transition:all .3s cubic-bezier(.25,.8,.25,1);display:flex;position:relative}.orioris-link-cover{z-index:20;position:absolute;inset:0;text-decoration:none!important}.box-title{margin-bottom:5px;font-size:1.1em;font-weight:800;display:block}.box-desc{color:#8b949e;font-size:.8em;line-height:1.4;display:block}@keyframes orioris-pulse{0%,to{transform:translateY(-5px)scale(1.01)}50%{transform:translateY(-5px)scale(1.02)}}.orioris-box:hover{z-index:10;background:#ffffff0d;animation:2s ease-in-out infinite orioris-pulse}.neon-red{border-top:3px solid #ff003c}.neon-red .box-title{color:#ff003c}.neon-red:hover{border-color:#ff003c;box-shadow:0 0 15px #ff003c80}.neon-orange{border-top:3px solid #f50}.neon-orange .box-title{color:#f50}.neon-orange:hover{border-color:#f50;box-shadow:0 0 15px #ff550080}.neon-yellow{border-top:3px solid #f2ce5a}.neon-yellow .box-title{color:#f2ce5a}.neon-yellow:hover{border-color:#f2ce5a;box-shadow:0 0 15px #f2ce5a80}.neon-blue{border-top:3px solid #58a6ff}.neon-blue .box-title{color:#58a6ff}.neon-blue:hover{border-color:#58a6ff;box-shadow:0 0 15px #58a6ff80}.neon-green{border-top:3px solid #00ff41}.neon-green .box-title{color:#00ff41}.neon-green:hover{border-color:#00ff41;box-shadow:0 0 15px #00ff4180}.neon-purple{border-top:3px solid #b392f0}.neon-purple .box-title{color:#b392f0}.neon-purple:hover{border-color:#b392f0;box-shadow:0 0 15px #b392f080}.neon-grey{border-top:3px solid #d0d7de}.neon-grey .box-title{color:#d0d7de}.neon-grey:hover{border-color:#d0d7de;box-shadow:0 0 15px #d0d7de80}#orioris-tinder-app{--bg:#1a1a2e;--card-bg:#161b22;--text:#fff;--accent:#f2ce5a;--green:#00ff41;--red:#f33;--blue:#58a6ff;background-color:var(--bg);color:var(--text);box-sizing:border-box;border:1px solid #30363d;border-radius:12px;flex-direction:column;justify-content:center;align-items:center;width:100%;min-height:80vh;padding:20px;font-family:Inter,sans-serif;display:flex}#orioris-tinder-app #game-container{text-align:center;flex-direction:column;align-items:center;width:100%;max-width:500px;display:flex}#orioris-tinder-app .progress-container{background-color:#30363d;border-radius:10px;width:100%;height:10px;margin-bottom:20px;overflow:hidden}#orioris-tinder-app .progress-bar{background-color:var(--accent);width:0%;height:100%;transition:width .3s}#orioris-tinder-app .card{background-color:var(--card-bg);cursor:default;-webkit-user-select:none;user-select:none;box-sizing:border-box;border:2px solid #30363d;border-radius:20px;justify-content:center;align-items:center;width:100%;min-height:180px;margin-bottom:30px;padding:40px 20px;font-size:1.5rem;font-weight:700;transition:transform .2s,border-color .2s;display:flex;position:relative;box-shadow:0 10px 30px #00000080}#orioris-tinder-app .new-badge{background:var(--accent);color:#000;border-radius:10px;padding:5px 10px;font-size:.7rem;font-weight:900;position:absolute;top:-10px;right:-10px;transform:rotate(5deg)}#orioris-tinder-app .controls{grid-template-columns:1fr 1fr 1fr;gap:15px;width:100%;display:grid}#orioris-tinder-app .btn{cursor:pointer;color:#fff;border:none;border-radius:12px;flex-direction:column;align-items:center;padding:15px;font-size:1.2rem;font-weight:700;transition:transform .1s;display:flex}#orioris-tinder-app .btn:active{transform:scale(.95)}#orioris-tinder-app .btn-no{background-color:var(--red);color:#fff}#orioris-tinder-app .btn-dev{background-color:var(--blue);color:#000}#orioris-tinder-app .btn-yes{background-color:var(--green);color:#000}#orioris-tinder-app .btn-stop{color:#aaa;cursor:pointer;background:0 0;border:1px solid #555;border-radius:8px;margin-top:25px;padding:10px 20px;font-size:.9rem}#orioris-tinder-app .btn-stop:hover{border-color:var(--accent);color:var(--accent)}#orioris-tinder-app .key-hint{opacity:.7;margin-top:5px;font-size:.7rem;font-weight:400}#orioris-tinder-app #results-container{background:var(--card-bg);border:1px solid #30363d;border-radius:15px;width:100%;max-width:800px;max-height:70vh;padding:30px;display:none;overflow-y:auto}#orioris-tinder-app .result-group{text-align:left;margin-bottom:30px}#orioris-tinder-app .result-group h3{color:var(--accent);border-bottom:2px solid #30363d;padding-bottom:10px}#orioris-tinder-app .tag-cloud{flex-wrap:wrap;gap:10px;display:flex}#orioris-tinder-app .tag{background:#0d1117;border-radius:15px;padding:5px 12px;font-size:.9rem}#orioris-tinder-app .tag.yes{border:1px solid var(--green);color:var(--green)}#orioris-tinder-app .tag.dev{border:1px solid var(--blue);color:var(--blue)}#orioris-tinder-app .btn-copy{background-color:var(--accent);color:#000;cursor:pointer;border:none;border-radius:8px;width:100%;margin-top:20px;padding:15px 30px;font-size:1.2rem;font-weight:900}#orioris-tinder-app .btn-reset{color:var(--red);border:1px solid var(--red);cursor:pointer;background:0 0;border-radius:5px;margin-top:30px;padding:10px;font-size:.8rem}#orioris-tinder-app{--bg:#0d1117;--card-bg:#161b22;--surface:#161b22b8;--line:#30363d;--text:#f0f6fc;--muted:#8b949e;--accent:#b392f0;--green:#00ff41;--red:#ff003c;--blue:#58a6ff;--yellow:#f2ce5a;border:1px solid var(--line);-webkit-backdrop-filter:blur(2px);backdrop-filter:blur(2px);background:radial-gradient(circle at 90% 0,#b392f029,#0000 30%),#0d1117ad;border-radius:16px;min-height:auto;padding:clamp(18px,4vw,42px);display:block;box-shadow:0 18px 45px #00000047}#orioris-tinder-app button{font:inherit}#orioris-tinder-app .tinder-hero{text-align:center;max-width:760px;margin:0 auto 30px}#orioris-tinder-app .tinder-back{border:1px solid var(--line);color:var(--muted);background:var(--surface);border-radius:8px;margin-bottom:24px;padding:7px 13px;text-decoration:none;transition:all .2s;display:inline-flex}#orioris-tinder-app .tinder-back:hover{color:var(--accent);border-color:var(--accent);transform:translate(-3px)}#orioris-tinder-app .tinder-kicker{color:var(--accent);letter-spacing:.15em;margin:0 0 9px;font:800 .74rem/1.3 JetBrains Mono,monospace}#orioris-tinder-app .tinder-hero h1{color:var(--text);margin:0;font-size:clamp(2rem,5vw,3.35rem);line-height:1.05}#orioris-tinder-app .tinder-hero>p:last-child{max-width:660px;color:var(--muted);margin:14px auto 0;line-height:1.6}#orioris-tinder-app .tinder-hero strong{color:var(--green)}#orioris-tinder-app #game-container{max-width:860px}#orioris-tinder-app .tinder-progress-head{width:100%;color:var(--text);justify-content:space-between;gap:12px;font:700 .82rem/1.3 JetBrains Mono,monospace;display:flex}#orioris-tinder-app .tinder-progress-head span:last-child{color:var(--accent)}#orioris-tinder-app .progress-container{border:1px solid var(--line);background:#21262d;height:8px;margin:10px 0 0}#orioris-tinder-app .progress-bar{background:linear-gradient(90deg, var(--accent), var(--green));box-shadow:0 0 12px #00ff4173}#orioris-tinder-app .tinder-progress-note{width:100%;color:var(--muted);text-align:left;margin:8px 0 22px;font-size:.78rem}#orioris-tinder-app .family-nav{grid-template-columns:repeat(5,minmax(0,1fr));gap:9px;width:100%;margin:0 0 24px;display:grid}#orioris-tinder-app .family-card{text-align:left;min-height:78px;color:var(--muted);background:var(--surface);border:1px solid var(--line);border-top:3px solid var(--card-color,var(--line));cursor:pointer;border-radius:10px;padding:10px 8px;transition:transform .2s,border-color .2s,box-shadow .2s}#orioris-tinder-app .family-card span,#orioris-tinder-app .family-card strong,#orioris-tinder-app .family-card small{display:block}#orioris-tinder-app .family-card span{font-size:1.05rem}#orioris-tinder-app .family-card strong{color:var(--text);margin-top:3px;font-size:.78rem}#orioris-tinder-app .family-card small{margin-top:4px;font:.68rem JetBrains Mono,monospace}#orioris-tinder-app .family-card:hover,#orioris-tinder-app .family-card.active{border-color:var(--card-color);box-shadow:0 0 16px var(--card-glow);transform:translateY(-3px)}#orioris-tinder-app .purple{--card-color:#b392f0;--card-glow:#b392f059}#orioris-tinder-app .green{--card-color:#00ff41;--card-glow:#00ff4147}#orioris-tinder-app .red{--card-color:#ff003c;--card-glow:#ff003c47}#orioris-tinder-app .blue{--card-color:#58a6ff;--card-glow:#58a6ff47}#orioris-tinder-app .yellow{--card-color:#f2ce5a;--card-glow:#f2ce5a40}#orioris-tinder-app .tinder-card-meta{min-height:21px;color:var(--accent);letter-spacing:.07em;margin-bottom:7px;font:800 .75rem/1.3 JetBrains Mono,monospace}#orioris-tinder-app .card{width:min(100%,650px);min-height:236px;color:var(--text);border:1px solid var(--line);background:linear-gradient(145deg,#ffffff0f,#0000),#161b22b8;border-radius:16px;margin:0 auto 24px;padding:36px;font-size:clamp(1.5rem,3.5vw,2.35rem);line-height:1.25;box-shadow:0 16px 36px #0000003d}#orioris-tinder-app .card:hover{border-color:var(--accent);transform:translateY(-4px);box-shadow:0 0 24px #b392f038}#orioris-tinder-app .card small{color:var(--muted);margin-top:13px;font-size:.8rem;font-weight:400;display:block}#orioris-tinder-app .card.vote-no{border-color:var(--red)}#orioris-tinder-app .card.vote-dev{border-color:var(--blue)}#orioris-tinder-app .card.vote-yes{border-color:var(--green)}#orioris-tinder-app .controls{gap:10px;width:min(100%,650px)}#orioris-tinder-app .btn{min-height:77px;color:var(--text);background:var(--surface);border:1px solid var(--line);text-transform:uppercase;letter-spacing:.04em;border-radius:10px;gap:3px;padding:10px;font-size:.88rem;transition:transform .16s,box-shadow .16s,border-color .16s}#orioris-tinder-app .btn span{font-size:1.35rem;line-height:1}#orioris-tinder-app .btn kbd{color:var(--muted);border:1px solid;border-radius:4px;padding:2px 5px;font:.68rem JetBrains Mono,monospace}#orioris-tinder-app .btn:hover{transform:translateY(-3px)}#orioris-tinder-app .btn-no{color:var(--red)}#orioris-tinder-app .btn-no:hover{border-color:var(--red);box-shadow:0 0 18px #ff003c47}#orioris-tinder-app .btn-dev{color:var(--blue)}#orioris-tinder-app .btn-dev:hover{border-color:var(--blue);box-shadow:0 0 18px #58a6ff47}#orioris-tinder-app .btn-yes{color:var(--green)}#orioris-tinder-app .btn-yes:hover{border-color:var(--green);box-shadow:0 0 18px #00ff4147}#orioris-tinder-app .tinder-actions{flex-direction:column;align-items:center;gap:10px;margin-top:18px;display:flex}#orioris-tinder-app .btn-stop{color:var(--muted);border:1px solid var(--line);background:0 0;border-radius:8px;margin:0;padding:9px 15px}#orioris-tinder-app .btn-stop:hover{color:var(--accent);border-color:var(--accent)}#orioris-tinder-app #save-msg,#orioris-tinder-app #copy-feedback{opacity:0;color:var(--green);font-size:.78rem;transition:opacity .2s}#orioris-tinder-app #save-msg.visible,#orioris-tinder-app #copy-feedback.visible{opacity:1}#orioris-tinder-app #results-container{background:0 0;border:0;max-width:100%;max-height:none;padding:0;overflow:visible}#orioris-tinder-app .results-heading{text-align:center}#orioris-tinder-app .results-heading h2{color:var(--text);margin:0}#orioris-tinder-app .results-heading p:last-child{color:var(--muted)}#orioris-tinder-app .results-actions{justify-items:center;gap:8px;margin:21px 0 30px;display:grid}#orioris-tinder-app .btn-copy{color:#0d1117;background:var(--accent);border-radius:9px;width:auto;margin:0;padding:13px 20px;box-shadow:0 0 20px #b392f040}#orioris-tinder-app .btn-copy:hover{filter:brightness(1.12);transform:translateY(-2px)}#orioris-tinder-app .family-results{grid-template-columns:repeat(2,minmax(0,1fr));gap:12px;display:grid}#orioris-tinder-app .family-result{background:var(--surface);border:1px solid var(--line);border-top:3px solid var(--card-color);border-radius:10px;padding:14px}#orioris-tinder-app .family-result>div:first-child{grid-template-columns:28px 1fr;align-items:center;gap:2px;display:grid}#orioris-tinder-app .family-result span{grid-row:span 2;font-size:1.2rem}#orioris-tinder-app .family-result strong{color:var(--text)}#orioris-tinder-app .family-result small{color:var(--muted);font-size:.72rem}#orioris-tinder-app .result-meter{background:#21262d;border-radius:10px;height:6px;margin:12px 0 7px;overflow:hidden}#orioris-tinder-app .result-meter i{background:var(--card-color);height:100%;box-shadow:0 0 10px var(--card-glow);display:block}#orioris-tinder-app .family-result p{color:var(--muted);margin:0;font-size:.75rem}#orioris-tinder-app .family-result p b{color:var(--card-color)}#orioris-tinder-app .results-columns{grid-template-columns:repeat(2,minmax(0,1fr));gap:16px;margin-top:30px;display:grid}#orioris-tinder-app .result-group{background:var(--surface);border:1px solid var(--line);border-radius:10px;padding:18px}#orioris-tinder-app .result-group h3{margin-top:0;font-size:1rem}#orioris-tinder-app .dev-group h3{color:var(--blue)}#orioris-tinder-app .yes-group h3{color:var(--green)}#orioris-tinder-app .tag{background:#0d1117;font-size:.8rem}#orioris-tinder-app .tinder-footer-actions{justify-content:center;gap:12px;margin-top:28px;display:flex}#orioris-tinder-app .resume{color:var(--green);border-color:var(--green)}#orioris-tinder-app .btn-reset{border-radius:8px;margin:0}@media screen and (max-width:700px){#orioris-tinder-app{padding:18px 12px}#orioris-tinder-app .family-nav{grid-template-columns:repeat(2,minmax(0,1fr))}#orioris-tinder-app .family-card{min-height:66px}#orioris-tinder-app .card{min-height:190px;padding:24px 18px}#orioris-tinder-app .controls{gap:7px}#orioris-tinder-app .btn{min-height:70px;font-size:.68rem}#orioris-tinder-app .family-results,#orioris-tinder-app .results-columns{grid-template-columns:1fr}#orioris-tinder-app .tinder-footer-actions{flex-direction:column;align-items:center}}.mermaid{box-sizing:border-box;border-radius:14px;justify-content:center;align-items:center;transition:background-color .3s,box-shadow .3s;display:flex;position:relative;left:50%;overflow-x:auto;transform:translate(-50%);width:100vw!important;max-width:1000px!important;margin:3rem 0!important;padding:1rem!important}.mermaid svg{width:100%!important;height:auto!important;max-height:65vh!important}.mermaid .nodeLabel{font-size:1rem!important}:root[saved-theme=light] .mermaid{background-color:#f4f6f8db;box-shadow:inset 0 0 0 1px #161b221a}.spin-active{transform-origin:50%;animation:15s linear infinite spin-3d}@keyframes spin-3d{0%{transform:rotateY(0)}to{transform:rotateY(360deg)}}:root[saved-theme=light] img.spin-active{filter:invert()!important}@keyframes flux-rapide{0%{background-position:200% 0;width:0%}to{background-position:0 0;width:100%}}@keyframes pulse-glow{0%,to{box-shadow:0 0 5px #00ff4180}50%{box-shadow:0 0 20px #00ff41cc}}.orioris-progress-container{box-sizing:border-box;background:#161b22;border:1px solid #30363d;border-radius:6px;width:100%;height:24px;margin:15px 0;position:relative;overflow:hidden}.orioris-progress-fill{background:linear-gradient(90deg,#f05,#00ff41,#f05) 0 0/200% 100%;border-radius:6px;width:0%;height:100%;animation:20s linear infinite flux-rapide,1.5s ease-in-out infinite pulse-glow}.orioris-progress-text{color:#fff;letter-spacing:2px;text-shadow:0 0 8px #000;white-space:nowrap;pointer-events:none;justify-content:center;align-items:center;width:100%;height:100%;font-size:.8em;font-weight:900;display:flex;position:absolute;top:0;left:0}@keyframes gyro-spin{0%{transform:translate(-50%,-50%)rotate(0)}to{transform:translate(-50%,-50%)rotate(360deg)}}@keyframes emergency-flash{0%,to{opacity:1;transform:scale(1)}50%{opacity:.8;transform:scale(.98)}}.orioris-idea-widget{--idea-accent:#58a6ff;width:100%;max-width:980px;margin:2.5rem auto}.orioris-idea-panel{border:1px solid color-mix(in srgb, var(--idea-accent) 55%, var(--lightgray));background:color-mix(in srgb, var(--light) 90%, transparent);border-radius:16px;overflow:hidden;box-shadow:0 12px 32px #0000001f}.orioris-idea-panel>summary{cursor:pointer;border-left:4px solid var(--idea-accent);grid-template-columns:minmax(0,1fr) auto;align-items:center;gap:.25rem 1rem;padding:1.25rem 1.4rem;list-style:none;display:grid}.orioris-idea-panel>summary::-webkit-details-marker{display:none}.orioris-idea-panel>summary:after{content:"+";color:var(--idea-accent);grid-area:1/2/span 3;font-size:1.8rem;font-weight:800;line-height:1}.orioris-idea-panel[open]>summary:after{content:"−"}.orioris-idea-panel>summary strong{color:var(--dark);font-size:1.1rem}.orioris-idea-panel>summary small{color:var(--gray)}.orioris-idea-kicker{color:var(--idea-accent);font-family:var(--codeFont);letter-spacing:.13em;font-size:.72rem;font-weight:800}.orioris-idea-content{border-top:1px solid var(--lightgray);padding:0 1.4rem 1.4rem}.orioris-idea-content>p{color:var(--darkgray)}.orioris-idea-form{gap:1rem;display:grid}.orioris-idea-grid{grid-template-columns:repeat(2,minmax(0,1fr));gap:1rem;display:grid}.orioris-idea-form label{color:var(--dark);gap:.4rem;font-weight:700;display:grid}.orioris-idea-form label span{color:var(--gray);font-size:.8rem;font-weight:500}.orioris-idea-form input,.orioris-idea-form select,.orioris-idea-form textarea{box-sizing:border-box;border:1px solid var(--lightgray);background:var(--light);width:100%;color:var(--darkgray);font:inherit;border-radius:9px;padding:.78rem .9rem;font-weight:500}.orioris-idea-form textarea{resize:vertical;min-height:6rem}.orioris-idea-form input:focus,.orioris-idea-form select:focus,.orioris-idea-form textarea:focus{outline:2px solid color-mix(in srgb, var(--idea-accent) 70%, transparent);outline-offset:2px;border-color:var(--idea-accent)}.orioris-idea-privacy{color:var(--gray);margin:0;font-size:.82rem}.orioris-idea-actions{flex-wrap:wrap;gap:.75rem;display:flex}.orioris-idea-actions button{border:1px solid var(--idea-accent);cursor:pointer;font:inherit;border-radius:9px;margin:0;padding:.75rem 1rem;font-weight:800}.orioris-idea-actions button[type=submit]{background:var(--idea-accent);color:#0d1117}.orioris-idea-copy{color:var(--dark);background:0 0}.orioris-idea-actions button:hover{filter:brightness(1.08);transform:translateY(-1px)}.orioris-idea-fallback{color:var(--gray);margin:0;font-size:.85rem}.orioris-idea-fallback a{color:var(--idea-accent);overflow-wrap:anywhere;font-weight:800}.orioris-idea-status{min-height:1.3em;color:var(--gray);margin:0;font-size:.85rem}.orioris-idea-status[data-state=success]{color:#117f37}.orioris-idea-status[data-state=error]{color:#cf222e}@media screen and (max-width:700px){.orioris-idea-grid{grid-template-columns:1fr}.orioris-idea-panel>summary{padding:1rem}.orioris-idea-content{padding:0 1rem 1rem}.orioris-idea-actions{flex-direction:column}.orioris-idea-actions button{width:100%}}